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Creatine improves physical performance but does not necessarily reduce inflammation, finds study

Wednesday, May 20th, 2026

Creatine, one of the most popular supplements among gym-goers and athletes, does not appear to have the anti-inflammatory effect that many imagine. This conclusion comes from a systematic review and meta-analysis conducted in Brazil by researchers at São Paulo State University (UNESP), which evaluated clinical trials in humans. The study indicates that, to date, there is no consistent evidence that creatine reduces inflammatory markers in the body.

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