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Corticosteroid use does not appear to increase infectious complications in non-COVID-19 pneumonia

Wednesday, December 3rd, 2025

A systematic review and meta-analysis evaluated the association between corticosteroid therapy, mortality, and infectious complications in adults with severe non-COVID-19 pneumonia or acute respiratory distress syndrome (ARDS). The review found that adjunct corticosteroids probably reduce short-term mortality in cases of severe pneumonia and ARDS and may reduce secondary shock in severe pneumonia. The findings are published in Annals of Internal Medicine.

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