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New insights into the role of stellate cells and blood vessels in the aging pancreas

Tuesday, October 14th, 2025

As age increases, the pancreas changes, which increases the risk of metabolic diseases such as type 2 diabetes, digestive disorders, and also cancer. Researchers at the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) have now been able to show in an animal model that stellate cells, in interaction with blood vessels, play a key role in age-related changes in the pancreas. They published their results in the journal Redox Biology.

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