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From 7,000 drugs to one active against resistant strains: AI advances pneumonia drug repurposing

Thursday, September 17th, 2026

Streptococcus pneumoniae is a bacterial pathogen that causes life-threatening infections, including pneumonia and meningitis. These infections are commonly treated with antibiotics, but antibiotics are becoming less effective against S. pneumoniae over time because of changes in the pathogen that cause drug resistance. This phenomenon, called antimicrobial resistance, is resulting in significant health care costs and deaths around the world. In a new study published by Wiley in Advanced Science, researchers used artificial intelligence (AI) to identify approved drugs that may be effective against S. pneumoniae.

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